​Carroll Laboratory

Department of Biological Sciences

Ohio University

Dr. Carroll's publications in PubMed


http://www.ncbi.nlm.nih.gov/pubmed/?term=carroll+rk

Wiemels R.E., Cech S.M., Meyer N.M., Burke C.A., Weiss A., Parks A.R., Shaw L.N., Carroll R.K.  (2017).  An intracellular peptidyl-prolyl cis/trans isomerase (PPIase) is required for folding and activity of the Staphylococcus aureus secreted virulence factor nuclease.  J Bacteriol 199:e00453-16

Tu N., Carroll R.K., Weiss A., Shaw L.N., Nicolas G., Thomas S., Lima A., Anderson B.  (2016).  A family of genus-specific RNAs in tandem with DNA-binding proteins control expression of the badA major virulence factor gene in Bartonella henselae. MicrobiologyOpen doi:10.1002/mbo3.420


Mashruwala A.A., Roberts C., Bhatt S., May K.L., Carroll R.K., Shaw L.N., Boyd J.M.  (2016).  Staphylococcus aureus SufT: an essential iron-sulphur cluster assembly factor in cells experiencing a high-demand for lipoic acid.  Mol Microbiol 102:1099-1119


Carroll R.K, Weiss A., Broach W.H., Wiemels R.E., Mogen A.B., Rice K.C., Shaw L.N. (2016). Genome-wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus. mBio 7:e01990-01915.


Carroll R.K., Weiss A., Shaw L.N. (2016). RNA-Sequencing of Staphylococcus aureus Messenger RNA. Methods Mol Biol 1373:131-141.

Lyons S.T., Wright C.A., Krute C.N., Rivera F.E., Carroll R.K., Shaw L.N. (2016). Confirming Sterility of an Autoclaved Infected Femoral Component for Use in an Articulated Antibiotic Knee Spacer: A Pilot Study. J Arthroplasty 31:245-9


Morgan J.K., Carroll R.K., Harro C.M., Vendura K.W., Shaw L.N., Riordan J.T. (2015). Global regulator of virulence A (GrvA) coordinates expression of discrete pathogenic mechanisms in enterohemorrhagic Escherichia coli through interactions with GadW-GadE. J Bacteriol 198:394-409


Krute, C. N., R. K. Carroll, F. E. Rivera, A. Weiss, R. M. Young, A. Shilling, M. Botlani, S. Varma, B. J. Baker, & L. N. Shaw, (2015) The disruption of prenylation leads to pleiotropic rearrangements in cellular behavior in Staphylococcus aureus.  Mol Microbiol 95: 819-832   

Burda, W. N., H. K. Miller, C. N. Krute, S. L. Leighton, R. K. Carroll, & L. N. Shaw, (2014)  Investigating the Genetic Regulation of the ECF-Sigma Factor σS in Staphylococcus aureus.  BMC Microbiol 14: 280

Mitra, A., P. A. Fay, K. W. Vendura, Z. Alla, R. K. Carroll, L. N. Shaw, & J. T. Riordan (2014)  σN-dependent control of acid resistance and the locus of enterocyte effacement (LEE) in enterohemorrhagic Escherichia coli is activated by acetyl phosphate in a manner requiring flagellar regulator FlhDC and the σS antagonist FliZ.  MicrobiologyOpen 3: 497-512.

Carroll, R. K., F. E. Rivera, C. K. Cavaco, G. M. Johnson, D. Martin & L. N. Shaw (2014)  The lone C-terminal processing protease in Staphylococcus aureus is localized to the cell wall and required for virulence.  Microbiology  160: 1737-1748.

Weiss, A., J. A. Ibarra, J. Paoletti, R. K. Carroll, & L. N. Shaw, (2014) The δ subunit of RNA polymerase guides promoter selectivity and virulence in Staphylococcus aureus. Infect Immun 82: 1424-1435.

Flores, A. R., R. J. Olsen, A. Wunsche, M. Kumaraswami, S. A. Shelburne 3rd, R. K. Carroll & J. M. Musser, (2013) Natural variation in the promoter of the gene encoding the Mga regulator alters host-pathogen interaction in group A Streptococcus carrier strains.  Infect Immun 81: 4128-4138.

Carroll, R. K., W. N. Burda, J. C. Roberts, K. K. Peak, A. C. Cannons & L. N. Shaw, (2013) Draft genome sequence of strain CBD-635: a Methicillin Resistant Staphylococcus aureus USA100 isolate.  Genome Announc 1: e00491-13.

Ibarra, J. A., E. Perez-Rueda, R. K. Carroll & L. N. Shaw, (2013) Global Analysis of Transcriptional Regulators in Staphylococcus aureus.  BMC Genomics 14: 126.

Carroll, R. K., F. Veillard, D. T. Gagne, J. M. Lindenmuth, M. Poreba, M. Drag, J. Potempa & L. N. Shaw, (2013) The Staphylococcus aureus leucine aminopeptidase LAP is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine.  Biol Chem 394: 791-803.

Miller, H. K., R. K. Carroll, W. N. Burda, C. N. Krute, J. E. Davenport & L. N. Shaw, (2012) The extracytoplasmic function sigma factor σS protects against both intracellular and extracytoplasmic stresses in Staphylococcus aureus. J Bacteriol 194: 4342-4354.

Carroll, R. K., T. M. Robison, F. E. Rivera, J. E. Davenport, I. M. Jonsson, D. Florczyk, A. Tarkowski, J. Potempa, J. Koziel & L. N. Shaw, (2012) Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus. Microbes Infect 14: 989-999.

Carroll, R. K., S. B. Beres, I. Sitkiewicz, L. Peterson, R. K. Matsunami, D. A. Engler, A. R. Flores, P. Sumby & J. M. Musser, (2011) Evolution of diversity in epidemics revealed by analysis of the human bacterial pathogen group A Streptococcus. Epidemics 3: 159-170.

Prosen, K. R., R. K. Carroll, W. N. Burda, C. N. Krute, B. Bhattacharya, M. L. Dao, E. Turos & L. N. Shaw, (2011) The impact of fatty acids on the antibacterial properties of N-thiolated beta-lactams. Bioorg Med Chem Lett 21: 5293-5295.

Carroll, R. K. & J. M. Musser, (2011) From transcription to activation: how group A streptococcus, the flesh-eating pathogen, regulates SpeB cysteine protease production. Mol Microbiol 81: 588-601.

Carroll, R. K., S. A. Shelburne, 3rd, R. J. Olsen, B. Suber, P. Sahasrabhojane, M. Kumaraswami, S. B. Beres, P. R. Shea, A. R. Flores & J. M. Musser, (2011) Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice. J Clin Invest 121: 1956-1968.

Olsen, R. J., M. Ashraf, V. E. Gonulal, A. A. Ayeras, C. Cantu, P. R. Shea, R. K. Carroll, T. Humbird, J. L. Greaver, J. L. Swain, E. Chang, W. Ragasa, L. Jenkins, K. P. Lally, T. Blasdel, P. Cagle & J. M. Musser, (2010) Lower respiratory tract infection in cynomolgus macaques (Macaca fascicularis) infected with group A Streptococcus. Microb Pathog 49: 336-347.

Beres, S. B., R. K. Carroll, P. R. Shea, I. Sitkiewicz, J. C. Martinez-Gutierrez, D. E. Low, A. McGeer, B. M. Willey, K. Green, G. J. Tyrrell, T. D. Goldman, M. Feldgarden, B. W. Birren, Y. Fofanov, J. Boos, W. D. Wheaton, C. Honisch & J. M. Musser, (2010) Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics. Proc Natl Acad Sci U S A 107: 4371-4376.

Shelburne, S. A., 3rd, D. B. Keith, M. T. Davenport, S. B. Beres, R. K. Carroll & J. M. Musser, (2009) Contribution of AmyA, an extracellular alpha-glucan degrading enzyme, to group A streptococcal host-pathogen interaction. Mol Microbiol 74: 159-174.

Carroll, R. K., X. Liao, L. K. Morgan, E. M. Cicirelli, Y. Li, W. Sheng, X. Feng & L. J. Kenney, (2009) Structural and functional analysis of the C-terminal DNA binding domain of the Salmonella typhimurium SPI-2 response regulator SsrB. J Biol Chem 284: 12008-12019.

Walthers, D., R. K. Carroll, W. W. Navarre, S. J. Libby, F. C. Fang & L. J. Kenney, (2007) The response regulator SsrB activates expression of diverse Salmonella pathogenicity island 2 promoters and counters silencing by the nucleoid-associated protein H-NS. Mol Microbiol 65: 477-493.

O'Croinin, T., R. K. Carroll, A. Kelly & C. J. Dorman, (2006) Roles for DNA supercoiling and the Fis protein in modulating expression of virulence genes during intracellular growth of Salmonella enterica serovar Typhimurium. Mol Microbiol 62: 869-882.

Kelly, A., M. D. Goldberg, R. K. Carroll, V. Danino, J. C. Hinton & C. J. Dorman, (2004)  A global role for Fis in the transcriptional control of metabolism and type III secretion in Salmonella enterica serovar Typhimurium. Microbiology 150: 2037-2053.

​Carroll Laboratory