​Carroll Laboratory

Department of Biological Sciences

Ohio University

Dr. Carroll's publications in PubMed


Wiemels R.E., Cech S.M., Meyer N.M., Burke C.A., Weiss A., Parks A.R., Shaw L.N., Carroll R.K.  (2017).  An intracellular peptidyl-prolyl cis/trans isomerase (PPIase) is required for folding and activity of the Staphylococcus aureus secreted virulence factor nuclease.  J Bacteriol 199:e00453-16

Tu N., Carroll R.K., Weiss A., Shaw L.N., Nicolas G., Thomas S., Lima A., Anderson B.  (2016).  A family of genus-specific RNAs in tandem with DNA-binding proteins control expression of the badA major virulence factor gene in Bartonella henselae. MicrobiologyOpen doi:10.1002/mbo3.420

Mashruwala A.A., Roberts C., Bhatt S., May K.L., Carroll R.K., Shaw L.N., Boyd J.M.  (2016).  Staphylococcus aureus SufT: an essential iron-sulphur cluster assembly factor in cells experiencing a high-demand for lipoic acid.  Mol Microbiol 102:1099-1119

Carroll R.K, Weiss A., Broach W.H., Wiemels R.E., Mogen A.B., Rice K.C., Shaw L.N. (2016). Genome-wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus. mBio 7:e01990-01915.

Carroll R.K., Weiss A., Shaw L.N. (2016). RNA-Sequencing of Staphylococcus aureus Messenger RNA. Methods Mol Biol 1373:131-141.

Lyons S.T., Wright C.A., Krute C.N., Rivera F.E., Carroll R.K., Shaw L.N. (2016). Confirming Sterility of an Autoclaved Infected Femoral Component for Use in an Articulated Antibiotic Knee Spacer: A Pilot Study. J Arthroplasty 31:245-9

Morgan J.K., Carroll R.K., Harro C.M., Vendura K.W., Shaw L.N., Riordan J.T. (2015). Global regulator of virulence A (GrvA) coordinates expression of discrete pathogenic mechanisms in enterohemorrhagic Escherichia coli through interactions with GadW-GadE. J Bacteriol 198:394-409

Krute, C. N., R. K. Carroll, F. E. Rivera, A. Weiss, R. M. Young, A. Shilling, M. Botlani, S. Varma, B. J. Baker, & L. N. Shaw, (2015) The disruption of prenylation leads to pleiotropic rearrangements in cellular behavior in Staphylococcus aureus.  Mol Microbiol 95: 819-832   

Burda, W. N., H. K. Miller, C. N. Krute, S. L. Leighton, R. K. Carroll, & L. N. Shaw, (2014)  Investigating the Genetic Regulation of the ECF-Sigma Factor σS in Staphylococcus aureus.  BMC Microbiol 14: 280

Mitra, A., P. A. Fay, K. W. Vendura, Z. Alla, R. K. Carroll, L. N. Shaw, & J. T. Riordan (2014)  σN-dependent control of acid resistance and the locus of enterocyte effacement (LEE) in enterohemorrhagic Escherichia coli is activated by acetyl phosphate in a manner requiring flagellar regulator FlhDC and the σS antagonist FliZ.  MicrobiologyOpen 3: 497-512.

Carroll, R. K., F. E. Rivera, C. K. Cavaco, G. M. Johnson, D. Martin & L. N. Shaw (2014)  The lone C-terminal processing protease in Staphylococcus aureus is localized to the cell wall and required for virulence.  Microbiology  160: 1737-1748.

Weiss, A., J. A. Ibarra, J. Paoletti, R. K. Carroll, & L. N. Shaw, (2014) The δ subunit of RNA polymerase guides promoter selectivity and virulence in Staphylococcus aureus. Infect Immun 82: 1424-1435.

Flores, A. R., R. J. Olsen, A. Wunsche, M. Kumaraswami, S. A. Shelburne 3rd, R. K. Carroll & J. M. Musser, (2013) Natural variation in the promoter of the gene encoding the Mga regulator alters host-pathogen interaction in group A Streptococcus carrier strains.  Infect Immun 81: 4128-4138.

Carroll, R. K., W. N. Burda, J. C. Roberts, K. K. Peak, A. C. Cannons & L. N. Shaw, (2013) Draft genome sequence of strain CBD-635: a Methicillin Resistant Staphylococcus aureus USA100 isolate.  Genome Announc 1: e00491-13.

Ibarra, J. A., E. Perez-Rueda, R. K. Carroll & L. N. Shaw, (2013) Global Analysis of Transcriptional Regulators in Staphylococcus aureus.  BMC Genomics 14: 126.

Carroll, R. K., F. Veillard, D. T. Gagne, J. M. Lindenmuth, M. Poreba, M. Drag, J. Potempa & L. N. Shaw, (2013) The Staphylococcus aureus leucine aminopeptidase LAP is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine.  Biol Chem 394: 791-803.

Miller, H. K., R. K. Carroll, W. N. Burda, C. N. Krute, J. E. Davenport & L. N. Shaw, (2012) The extracytoplasmic function sigma factor σS protects against both intracellular and extracytoplasmic stresses in Staphylococcus aureus. J Bacteriol 194: 4342-4354.

Carroll, R. K., T. M. Robison, F. E. Rivera, J. E. Davenport, I. M. Jonsson, D. Florczyk, A. Tarkowski, J. Potempa, J. Koziel & L. N. Shaw, (2012) Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus. Microbes Infect 14: 989-999.

Carroll, R. K., S. B. Beres, I. Sitkiewicz, L. Peterson, R. K. Matsunami, D. A. Engler, A. R. Flores, P. Sumby & J. M. Musser, (2011) Evolution of diversity in epidemics revealed by analysis of the human bacterial pathogen group A Streptococcus. Epidemics 3: 159-170.

Prosen, K. R., R. K. Carroll, W. N. Burda, C. N. Krute, B. Bhattacharya, M. L. Dao, E. Turos & L. N. Shaw, (2011) The impact of fatty acids on the antibacterial properties of N-thiolated beta-lactams. Bioorg Med Chem Lett 21: 5293-5295.

Carroll, R. K. & J. M. Musser, (2011) From transcription to activation: how group A streptococcus, the flesh-eating pathogen, regulates SpeB cysteine protease production. Mol Microbiol 81: 588-601.

Carroll, R. K., S. A. Shelburne, 3rd, R. J. Olsen, B. Suber, P. Sahasrabhojane, M. Kumaraswami, S. B. Beres, P. R. Shea, A. R. Flores & J. M. Musser, (2011) Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice. J Clin Invest 121: 1956-1968.

Olsen, R. J., M. Ashraf, V. E. Gonulal, A. A. Ayeras, C. Cantu, P. R. Shea, R. K. Carroll, T. Humbird, J. L. Greaver, J. L. Swain, E. Chang, W. Ragasa, L. Jenkins, K. P. Lally, T. Blasdel, P. Cagle & J. M. Musser, (2010) Lower respiratory tract infection in cynomolgus macaques (Macaca fascicularis) infected with group A Streptococcus. Microb Pathog 49: 336-347.

Beres, S. B., R. K. Carroll, P. R. Shea, I. Sitkiewicz, J. C. Martinez-Gutierrez, D. E. Low, A. McGeer, B. M. Willey, K. Green, G. J. Tyrrell, T. D. Goldman, M. Feldgarden, B. W. Birren, Y. Fofanov, J. Boos, W. D. Wheaton, C. Honisch & J. M. Musser, (2010) Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics. Proc Natl Acad Sci U S A 107: 4371-4376.

Shelburne, S. A., 3rd, D. B. Keith, M. T. Davenport, S. B. Beres, R. K. Carroll & J. M. Musser, (2009) Contribution of AmyA, an extracellular alpha-glucan degrading enzyme, to group A streptococcal host-pathogen interaction. Mol Microbiol 74: 159-174.

Carroll, R. K., X. Liao, L. K. Morgan, E. M. Cicirelli, Y. Li, W. Sheng, X. Feng & L. J. Kenney, (2009) Structural and functional analysis of the C-terminal DNA binding domain of the Salmonella typhimurium SPI-2 response regulator SsrB. J Biol Chem 284: 12008-12019.

Walthers, D., R. K. Carroll, W. W. Navarre, S. J. Libby, F. C. Fang & L. J. Kenney, (2007) The response regulator SsrB activates expression of diverse Salmonella pathogenicity island 2 promoters and counters silencing by the nucleoid-associated protein H-NS. Mol Microbiol 65: 477-493.

O'Croinin, T., R. K. Carroll, A. Kelly & C. J. Dorman, (2006) Roles for DNA supercoiling and the Fis protein in modulating expression of virulence genes during intracellular growth of Salmonella enterica serovar Typhimurium. Mol Microbiol 62: 869-882.

Kelly, A., M. D. Goldberg, R. K. Carroll, V. Danino, J. C. Hinton & C. J. Dorman, (2004)  A global role for Fis in the transcriptional control of metabolism and type III secretion in Salmonella enterica serovar Typhimurium. Microbiology 150: 2037-2053.

​Carroll Laboratory